Table 3.

Results of the Genetic Risk Score (GRS) in the Discovery and Replication Samples

			Difference Test
			Discovery Samples			Replication Samples
Threshold at P Value (P*)	No. of SNPs Having P< P*		No. of SNPs Having P< P*& Low LD (r2<0.2)		P Value	No. of SNPs Having P< P* & Low LD (r2<0.2)		P Value
.001	1302		1144		1.0×10–3	1097		1.7×10–3
.005	6706		6046		3.9×10–4	5876		2.8×10–4
.01	13023		11735		1.5×10–3	11416		2.0×10–3

P Value was calculated using Wilcoxon rank-sum test to examine different distributions of GRS between BP-II patients and healthy controls.