Table 1.
Descriptive Statistics of Study Subjects.
| All | MDDs | Controls | ||
|---|---|---|---|---|
| N | 37 | 18 | 19 | |
| Age | 36.9 ± 11.4 | 37.3 ± 11.2 | 36.5 ± 12.1 | t = −0.195; p = 0.846 |
| Sex (m/f) | 13/25 | 6/12 | 7/12 | χ2 = 0.117; p = 0.9897 |
| Education | 31% Advanced degrees 51% BA or AA 17% Some college | 29% Advanced degrees 53% BA or AA 18% Some college | 33% Advanced degrees 50% BA or AA 17% Some college | χ2 = 0.174; p = 0.917 |
| Current Tobacco Use | 18.9% | 22.2% | 15.7% | χ2 = 0.249; bp = 0.618 |
| BMI (kg/m2)a | 24.6 ± 4.1 | 24.7 ± 4.5 | 24.6 ± 3.8 | F = 0.021;p = 0.885 |
| Hippocampal Volume | 4.51 ± 0.68 | 4.41 ± 0.74 | 4.60 ± 0.61 | t = 0.842;p = 0.405 |
| Hamilton Depression | 19.5 ± 3.1 | N/A | ||
| Quick IDS | 8.2 ± 6.8 | 14.3 ± 4.2 | 2.4 ± 1.5 | t = −11.73; p = 0.00 |
| Serum cortisol (ng/mL) | 130 ± 81.2 | 127 ± 69.0 | 132 ± 93.1 | t = 0.185; p = 0.85 |
| DHEA (ng/mL)a | 125 ± 87.5 | 128 ± 81.8 | 123 ± 946 | F = 0.148, p = 0.70 |
| DHEAS (ng/mL)a | 178 ± 115 | 190 ± 126 | 167 ± 105 | F = 0.764, p = 0.39 |
| Cort/DHEAa | 1.32 ± 0.874 | 1.35 ± 0.856 | 1.30 ± 0.913 | F = 0.415, p = 0.524 |
| Cort/DHEASa | 0.927 ± 0.629 | 0.856 ± 0.426 | 0.995 ± 0.781 | F = 0.065 p = 0.801 |
Statistics were performed on normalized values, covarying for age and sex.
a
The mean and standard deviation for BMI, DHEA(S), and Cort/DHEA(S) shown in table are calculated from raw values.