Table 2.
Biomarkers | Model including all biomarkersa | ||
---|---|---|---|
Coefficient | Standard error | p value | |
AGP | 0.692 | 0.35 | 0.047 |
CP | 0.551 | 0.36 | 0.127 |
VCAM-1 | −0.228 | 0.38 | 0.553 |
LPGDS | 0.870 | 0.76 | 0.254 |
MCP-1 | −0.046 | 0.86 | 0.957 |
TF | 0.256 | 0.23 | 0.275 |
Model after variable selectionb | |||
AGP | 0.782 | 2.84 | 0.004 |
CP | 0.602 | 0.34 | 0.080 |
AGP, Alpha-1-acid glycoprotein; CP, ceruloplasmin; VCAM-1, vascular cell adhesion molecule-1; LPGDS, lipocalin-like prostaglandin D synthase; MCP-1, monocyte chemoattractant protein 1; TF, transferrin
AGP alpha-1-acid glycoprotein
a59 Cohort 1 patients included in the exploratory novel biomarker models including VCAM-1 due to a missing measurements
bModel selected after applying the ‘stepAIC’ function in R