Table 2.
BMI and lipid profiles in participants stratified by the type of haemoglobin variants.
| Parameter | Sickling phenotype | p value | ||
|---|---|---|---|---|
| AA | SC | SS | ||
| (n = 50) | (n = 12) | (n = 38) | ||
| BMI (kg/m 2) | 23.21 ± 4.50 | 20.48 ± 4.18∗ | 20.73 ± 3.26∗ | 0.009 |
| BMI, n (%) | 0.181 | |||
| Underweight | 9 (18.0) | 4 (33.3) | 11 (28.9) | |
| Normal | 26 (52.0) | 7 (58.3) | 23 (60.5) | |
| Overweight | 11 (22.0) | 0 (0.0) | 4 (10.5) | |
| Obese | 4 (8.0) | 1 (8.3) | 0 (0.0) | |
| Blood pressure (mmHg) | ||||
| SBP | 115.52 ± 5.17 | 107.92 ± 7.22∗ | 109.21 ± 8.47∗ | <0.0001 |
| DBP | 76.98 ± 5.98 | 70.42 ± 6.86∗ | 72.39 ± 6.91∗ | 0.001 |
| Lipid profile | ||||
| TC (mmol/L) | 4.20 ± 0.98 | 3.23 ± 0.81∗ | 3.74 ± 0.75∗ | 0.001 |
| TG (mmol/L) | 0.97 ± 0.41 | 0.99 ± 0.81 | 0.97 ± 0.63 | 0.989 |
| LDL-C (mmol/L) | 4.27 ± 2.02 | 1.86 ± 0.76 | 2.25 ± 0.68 | 0.581 |
| VLDL-C (mmol/L) | 0.44 ± 0.03 | 0.64 ± 0.20 | 0.57 ± 0.09 | 0.241 |
| HDL-C (mmol/L) | 1.50 ± 0.47 | 0.93 ± 0.31∗ | 1.06 ± 0.33∗ | <0.0001 |
| Non-HDL-C (mmol/L) | 2.68 ± 1.06 | 2.38 ± 0.78 | 2.70 ± 0.65 | 0.533 |
| TG/HDL ratio | 0.71 ± 0.36 | 2.71 ± 1.91∗ | 1.10 ± 0.19+ | 0.035 |
∗Significantly different from the control group (AA) (p < 0.05). +Significantly different from the group (SC) (p < 0.05).