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. 2017 Jan 1;38:1–12. doi: 10.1186/s41021-016-0055-7

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 10 — Colocalization of stem cell markers and DNA damage. Double-immunofluorescence staining of stem/progenitor cell markers (CD133 and OV6) and DNA lesions (8-oxodG and 8-nitroguanine) in cholangiocarcinoma tissues. White arrows indicate co-localization of DNA damage marker and stemness marker in cancer cells. Original magnification is × 400; Scale bar = 25 μm