Fig. 3.
The western blot study of inflammatory markers of IL-10 and TNF-alpha. Both IL-10 and TNF-alpha protein expression increased significantly in MCAO group as compared to that in sham group at 24 h after reperfusion (#p<0.05). Such elevations were reduced with SA (Figure 3A–B, Figure 3C, Figure 3D). MCAO, middel cerebral artery occlusion; SA, salvinorin A; KOR, kappa opioid receptor.