Fig. 5.
Western blotting analysis of the infarcted brain tissue. Both the original data (Figure 5A) and statitistal analysis (Figure 5B) showed that the expression levels of cleaved casepase-3 in the MCAO group significantly increased as compared to that in sham group (#p < 0.05). Administration of SA reduced the levels of cleaved casepase-3 proteins (*p < 0.05 vs MCAO), such effect was blocked by kappa opioid receptor antagonist nor-BNI. MCAO, middel cerebral artery occlusion; SA, salvinorin A;