Figure 2. Additive killing of B16-M05 and OVA-Panc02 tumor cells by OVA-specific (OT-I) CTLs and non-specific A-NK cells.
Cytotoxicity of mixtures of OVA-specific (OT-I) CTLs and A-NK cells was determined in standard four hour 51-Cr-release assays. CTLs and A-NK cells were mixed with tumor cells at ratios from 0:1 to 200:1 and 0:1 to 50:1, respectively. A: Percent specific lysis of B16-M05 tumor cells (representative of multiple experiments). B: Percent specific lysis of OVA-Panc02 tumor cells (representative of two experiments). Legend identifies A-NK cell:tumor cell ratios.