Table 3. Assignment of likely phenotypes (acetylation status) based on diplotypes of NAT2 alleles.
Likely phenotype | Genotype | Examples of diplotypes |
---|---|---|
Normal/high activity (rapid acetylator) | 2 rapid NAT2 alleles (*4, *11, *12, *13, *18) | *4/*4, *4/*12, *4/*13, etc. |
Intermediate activity (intermediate acetylator) | 1 rapid NAT2 allele and 1 slow NAT2 allele | *4/*5, *4/*6, *5/*11, *7/*11, *13/*14, etc |
Low activity (slow acetylator) | 2 slow NAT2 alleles (*5, *6, *7, *14) | *6/*6, *7/*7, *6/*7, *5/*6, *5/*7, etc. |