Table 1. Characteristics of enrolled patients.
Characteristics | Value (%) |
---|---|
Age (year, median) | 57 |
Sex ratio (male/female) | 2.36 (236/100) |
Community-acquired: Hospital-acquired | 242:94 |
Underlying diseases | |
Solid organ malignancy | 142 (42.3%) |
Hepatic cirrhosis | 132 (39.3%) |
Diabetes mellitus | 86 (25.6%) |
Leukemia | 24 (7.1%) |
Concomitant chemotherapy | 74 (22.0%) |
Clinical manifestations | |
Fever (>38℃) | 130 (38.7%) |
Hypothermia | 34 (10.1%) |
Shock | 86 (25.6%) |
Altered consciousness | 60 (17.9%) |
Abdominal pain | 52 (15.5%) |
Dyspnea | 48 (14.3%) |
Site of infection | |
Hepatobiliary infections | 170 (50.6%) |
Peritonitis | 62 (18.5%) |
Primary bacteremia | 60 (17.9%) |
Pneumonia | 20 (5.9) |
Skin and soft-tissue infection | 14 (4.2%) |
Catheter related infection | 10 (3.0%) |
Usage of Antimicrobial agent | |
Initial Appropriate : Inappropriate | 196:140 |
Combination therapy | 166 (49.4%) |
Duration of treatment (days, median) | 10 |
Number of patients in which antimicrobial agents were initiated within 6 h of symptom manifestation | 272 (81.0%) |