Table 1. Survival analysis according to T-lymphocyte markers using different cutoff levels in HER2-positive cancer defined by category of HER2 status from the Kaplan-Meier plotter.
Split patients | CD4 | CD8 | FOXP3 | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
No. of patients* | HR† | 95% CI | Log-rank p |
No. of patients* | HR† | 95% CI | Log-rank p |
No. of patients* | HR† | 95% CI | Log-rank p |
|
Lower quartile | 42:126 | 0.59 | 0.34–1.02 | 0.058 | 42:126 | 0.73 | 0.41–1.29 | 0.275 | 39:111 | 1.03 | 0.56–1.90 | 0.929 |
Lower tertile | 55:113 | 0.6 | 0.36–1.02 | 0.058 | 55:113 | 0.83 | 0.48–1.43 | 0.492 | 50:100 | 1.09 | 0.61–1.95 | 0.781 |
Median | 84:84 | 0.99 | 0.59–1.67 | 0.983 | 84:84 | 1.04 | 0.61–1.74 | 0.896 | 75:75 | 1.01 | 0.58–1.75 | 0.973 |
Upper tertile | 113:55 | 1.19 | 0.69–2.05 | 0.534 | 113:55 | 0.56 | 0.31–1.03 | 0.060 | 100:50 | 0.67 | 0.36–1.24 | 0.202 |
Upper quartile | 126:42 | 1.49 | 0.84–2.64 | 0.168 | 128:40 | 0.51 | 0.25–1.03 | 0.057 | 112:38 | 0.64 | 0.32–1.27 | 0.198 |
HER2=human epidermal growth factor receptor 2; HR=hazard ratio; CI=confidence interval.
*Number of patients was presented as patients having low expression versus those having high expression; †Hazard ratio of patients having high expression of biomarker.