Table 2. Survival analysis according to T-lymphocyte markers using different cutoff levels in HER2-positive subtype defined by category of intrinsic subtype from the Kaplan-Meier plotter.

Split patients	CD4				CD8				FOXP3
	No. of patients*	HR†	95% CI	Log-rank p	No. of patients*	HR†	95% CI	Log-rank p	No. of patients*	HR†	95% CI	Log-rank p
Lower quartile	52:156	0.57	0.37–0.89	0.013	52:156	0.41	0.27–0.64	< 0.001	38:111	0.76	0.45–1.28	0.294
Lower tertile	69:139	0.45	0.3–0.68	< 0.001	69:139	0.53	0.35–0.8	0.002	50:99	0.65	0.4–1.05	0.074
Median	104:104	0.52	0.34–0.79	0.002	104:104	0.52	0.34–0.8	0.003	74:75	0.64	0.4–1.03	0.063
Upper tertile	139:64	0.68	0.43–1.09	0.108	139:64	0.57	0.35–0.92	0.021	101:48	0.93	0.56–1.54	0.766
Upper quartile	156:52	0.62	0.36–1.06	0.076	156:52	0.57	0.33–0.98	0.038	114:35	0.74	0.41–1.33	0.315

HER2=human epidermal growth factor receptor 2; HR=hazard ratio; CI=confidence interval.

^*Number of patients was presented as patients having low expression versus those having high expression; ^†Hazard ratio of patients having high expression of biomarker.