Table 4. Independent predictors of chemotherapy induced left ventricular dysfunction.
Variable | RR | CI | p-value |
---|---|---|---|
Low BMI | 2.207 | 1.247–3.928 | 0.007 |
Triglyceride | 0.995 | 0.990–1.001 | 0.109 |
Advanced cancer stage | 1.782 | 1.067–2.974 | 0.027 |
LVEDD | 1.121 | 1.006–1.248 | 0.138 |
LVEF | 1.120 | 0.862–1.454 | 0.398 |
Chemotherapy cycle | 0.959 | 0.873–1.053 | 0.382 |
Doxorubicin therapy | 1.363 | 0.745–2.493 | 0.315 |
Paclitaxel therapy | 0.991 | 0.558–1.762 | 0.975 |
Trastuzumab therapy | 5.080 | 2.998–8.609 | < 0.001 |
Radiation therapy | 1.436 | 1.182–1.880 | 0.086 |
RR=relative risk; CI=confidence interval; BMI=body mass index; LVEDD=left ventricle end diastolic dimension; LVEF=left ventricular ejection fraction.