Table 2.
Correlation between expression of miR-375 or miR-205 and clinicopathologic features of LSCCs.
| Characteristics | miR-375 ↑ | miR-375 ↓ | p | miR-205 ↑ | miR-205 ↓ | p | |
|---|---|---|---|---|---|---|---|
| All samples | (40) | 20 | 20 | 20 | 20 | ||
| Age | 0.53 | 0.20 | |||||
| ≤60 | (22) | 12 | 10 | 9 | 13 | ||
| >60 | (18) | 8 | 10 | 11 | 7 | ||
| pT status | 0.02 | 0.33 | |||||
| Tis -T2 | (15) | 11 | 4 | 9 | 6 | ||
| T3 -T4 | (25) | 9 | 16 | 11 | 14 | ||
| pN status | 0.33 | 0.74 | |||||
| N0 | (25) | 14 | 11 | 12 | 13 | ||
| N > 0 | (15) | 6 | 9 | 8 | 7 | ||
| Clinical UICC stage | 0.01 | 0.29 | |||||
| Early stage (I-II) | (11) | 9 | 2 | 7 | 4 | ||
| Advanced stage (III-IV) | (29) | 11 | 18 | 13 | 16 | ||
| Pathological grade | 0.14 | 1.00 | |||||
| G1 | (10) | 7 | 3 | 5 | 5 | ||
| G2-G3 | (30) | 13 | 17 | 15 | 15 | ||
| Anatomic site | 0.08 | 0.01 | |||||
| Glottis+subglottis | (29) | 17 | 12 | 11 | 18 | ||
| Supraglottis | (11) | 3 | 8 | 9 | 2 |
All patients were staged according to the 2002 Union Form International Cancer Control (UICC) staging classification system for laryngeal cancer.