Table 1.
Subject characteristics
| GPA control subjects (n = 11) | MMTT control subjects (n = 10) | PS-CF (n = 9) | PI-CF (n = 11) | Overall P value |
|||
|---|---|---|---|---|---|---|---|
| Control subjects vs. PI-CF | Control subjects vs. PS-CF | PI-CF vs. PS-CF | |||||
| Demographics | |||||||
| Sex (female) | 5 (45) | 5 (50) | 6 (67) | 5 (45) | 0.80 | ||
| Age (years) | 25 (21–38) | 25 (20–41) | 31 (16–56) | 19 (16–50) | 0.13 | ||
| BMI (kg/m2) | 24 (21–29) | 24 (18–27) | 24 (19–33) | 22 (17–31) | 0.64 | ||
| HbA1c (%)# | N/D | 5.0 (4.7–5.5) | 5.2 (3.8–6.0) | 5.5 (5.3–6.2) | 0.004 | ||
| 0.0006* | 0.34* | 0.06* | |||||
| OGTT profile | |||||||
| Fasting glucose (mg/dL) | 82 (74–107) | 85 (68–94) | 87 (74–102) | 92 (73–98) | 0.18 | ||
| 1-h glucose (mg/dL) | 122 (70–199) | 114 (60–157) | 118 (67–165) | 162 (127–193) | 0.01 | ||
| 0.001&* | 0.35* | 0.009* | |||||
| 2-h glucose (mg/dL) | 95 (60–128) | 94 (74–111) | 104 (46–115) | 97 (66–134) | 0.90 | ||
Data are medians and ranges (min–max) for continuous variables and number and (percentage) for categorical variables.
*Between-group comparisons performed when overall P value was significant at P ≤ 0.05;
#to convert to mmol/mol, multiply by 10.93 and subtract 23.50;
&significant differences between PI-CF and MMTT control subjects.