Table 1.
Comparison of nomenclature systems
| Bush–Jacoby | Ambler | Defining substrates | Inhibited by EDTA | Inhibited by clavulanaic acid or tazobactam | Representatives |
|---|---|---|---|---|---|
| 1 | Class C | Cephalosporinases | (–) | No | P99 |
| Cephamycinases | FOX-4 | ||||
| 2 | Class A | (–) | Yes | ||
| 2a | Penicillins | Yes | PC1 | ||
| 2b | Yes | TEM-1, SHV-1 | |||
| 2be | Cephalosporins | Yes | TEM-10, SHV-2 | ||
| 2br | No | TEM-30 | |||
| 2ber | No | TEM-50 | |||
| 2ce | Yes | RTG-4 | |||
| 2d | Class D | Penicillins | (–) | Variable | OXA-1 |
| 2de | Cephalosporins | OXA-11 | |||
| 2df | Carbapenems | OXA-23 | |||
| 2e | Yes | CepA | |||
| 2f | Carbapenems | Variable | KPC-2 | ||
| 3 | Class B | Carbapenems | (+) | No | |
| 3a | B1 | NDM-1, VIM-2,IMP-1 | |||
| 3b | B2 | CphA | |||
| 3a | B3 | L1 |
Based on data from Bush and Jacoby (2010).
EDTA, ethylenediaminetetraacetate.