Table 2.

Association of NASH with any 30-day, perioperative (within 24 hours) or early postoperative (1–30 days) cardiovascular disease mortality following liver transplantation (OPTN, 2002–2011)

Characteristic	Any 30-day CVD mortality (N=492)		Perioperative CVD mortality (N=185)		Early postoperative CVD mortality (N=307)
	OR (95% CI)a	P value	OR (95% CI)	P value	OR (95% CI)	P value
Unadjusted	1.30 (1.02, 1.66)	0.037	1.64 (1.14, 2.37)	0.008	1.10 (0.80, 1.53)	0.562
Base Model	1.23 (0.96, 1.59)	0.108	1.43 (1.01, 2.01)	0.041	1.11 (0.79, 1.56)	0.537
Base + Pre-transplant Composite CVD	1.35 (0.93, 1.96)	0.119	1.35 (0.84, 2.17)	0.215	1.37 (0.84, 2.22)	0.212
Base + Pre-transplant Diabetes	1.22 (0.93, 1.58)	0.146	1.35 (0.94, 1.92)	0.100	1.13 (0.80, 1.59)	0.503
Base + Pre-transplant Renal Impairmentb	1.13 (0.87, 1.46)	0.355	1.29 (0.92, 1.82)	0.146	1.03 (0.73, 1.44)	0.873

^aLogistic regression

^beGFR ≤ 60 mL/min/1.73 m²

Base model: age, race, sex, education level, transplant center

Abbreviations: NASH, nonalcoholic steatohepatitis; CVD, cardiovascular disease; eGFR, estimated glomerular filtration rate