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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: J Pharmacokinet Pharmacodyn. 2016 Sep 19;43(5):481–504. doi: 10.1007/s10928-016-9492-y

Fig 1.

Fig 1

Physiologically-based pharmacokinetics models for special populations within the AAD2 (adopt, adapt, development, assess, amend, deliver) computation methodology, an iterative and integrative approach to model development