Table 1.

Zoonotic pathogens, their human diseases, vectors, and Peromyscus spp. Hosts

Microbe/parasite	Human disease	Vector/intermediate host	P. leucopus [references]	P. maniculatus [references]
Borrelia burgdorferi	Lyme disease (Lyme borreliosis)	Ixodes scapularis, I. pacificus ticks	+ a [21, 22, 77]	+ [28, 47]
Borrelia miyamotoi	Hard tick-borne relapsing fever	I. scapularis, I. pacificus	+ [34, 78]	?
Anaplasma phagocytophilum	Human granuclocytic anaplasmosis	I. scapularis, I. pacificus, I. spinipalpis	+ [79, 80]	+ [81]
Babesia microti	Babesiosis	I. scapularis	+ [82, 83]	–
Powassan/deer tick virus	Viral encephalitis	I. scapularis	+ [84]	+ [85]
Ehrlichia muris subsp. euclairensis	Ehrlichiosis	I. scapularis	+ [9, 12]	–
Sin Nombre-like hantaviruses	Hantavirus pulmonary syndrome	None	+ [86]	+ [87]
Yersinia pestis	Plague	Fleas	–	+ [4, 88]
Bartonella spp.	Bartonellosis	Fleas	+ [89]	+ [54, 55]
Borrelia bissettii	None known	I. pacificus, I. spinipalpis	–	+ [90, 91]
“Borrelia davisi”	None known	?	+ [92]	?
Trypanosoma sp.a	None known	?	+ [58]	+ [57]
Schistosomatium douthitti	None known	Snail	?	+ [56, 93]

^a+, the listed Peromyscus species is a reservoir; –, not a reservoir; ?, reservoir status not known

^bExclusive of agents of Chagas disease (T. cruzi) and African trypanosomiasis (T. brucei)