Table 2.

Brain regions showing a general age effect (main effect of age).

				MNI Coordinates
Region	Hemisphere	# Voxels	F	x	y	z
Age predicts less activation
vmPFC	L	395	31.23	−3	45	−9
Subgenual ACC	L	38	20.62	−9	36	−9
Subgenual ACC	M	53	21.22	0	30	−6
Pregenual ACC	R	56	28.40	3	30	3
Dorsal ACC	M	36	18.49	0	33	18
Caudate	L	41	29.23	−12	15	3
Caudate	L	24	24.21	−6	6	−3
Caudate	R	39	21.23	9	9	−6
Putamen	L	33	26.84	−18	12	−9
Amygdala	L	118	37.70	−27	−9	−15
Hippocampus	L	24	25.16	−21	−9	−27
Anterior insula	L	29	19.41	−42	6	−18
Amygdala	R	41	24.94	30	−3	−24
Superior temporal gyrus	L	33	20.26	−60	−24	0
Superior temporal gyrus	L	20	20.23	−51	−18	−3
Cerebellum	R	114	21.86	3	−57	−21
Cerebellum	R	32	21.82	9	−48	−18
Cerebellum	R	37	21.82	9	−48	−18
Age predicts more activation
Inferior and middle frontal gyri	L	31	23.57	−51	12	30
Inferior parietal lobule	L	52	28.78	−36	−39	33

Brain regions identified by the main effect of age (i.e., aversive and neutral stimuli compared to fixation). R = right, L = left, M = medial. For hemisphere, F = maximum F statistic for a given cluster. Subclusters that contained 20 or more voxels are reported under their supracluster.