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. 2016 Dec 23;32(4):187–193. doi: 10.5625/lar.2016.32.4.187

Table 1. Relationship between the number of tumor cells injected vs. tumor growth rate.

Cell line Injection no. (×106 cells/mouse) Number of mice Doubling time (day) Tumor growth rate (%/day) p-value
HCT116 1 5 7.2±1.0 10.5±1.5 0.207
2 7 5.8±0.6 13.0±1.7
3 23 5.5±0.5 13.7±0.7
HCT-8 1 14 5.7±0.6 14.6±2.0 0.5246
3 3 5.8±1.6 12.6±2.1
H460 3 42 2.9±0.2 26.7±1.0 0.0888
4 10 3.0±0.1 23.9±1.2
A549 2 18 13.3±1.5 6.4±0.6 0.6843
3 29 11.0±0.6 6.7±0.3