Table 1. Relationship between the number of tumor cells injected vs. tumor growth rate.
Cell line | Injection no. (×106 cells/mouse) | Number of mice | Doubling time (day) | Tumor growth rate (%/day) | p-value |
---|---|---|---|---|---|
HCT116 | 1 | 5 | 7.2±1.0 | 10.5±1.5 | 0.207 |
2 | 7 | 5.8±0.6 | 13.0±1.7 | ||
3 | 23 | 5.5±0.5 | 13.7±0.7 | ||
HCT-8 | 1 | 14 | 5.7±0.6 | 14.6±2.0 | 0.5246 |
3 | 3 | 5.8±1.6 | 12.6±2.1 | ||
H460 | 3 | 42 | 2.9±0.2 | 26.7±1.0 | 0.0888 |
4 | 10 | 3.0±0.1 | 23.9±1.2 | ||
A549 | 2 | 18 | 13.3±1.5 | 6.4±0.6 | 0.6843 |
3 | 29 | 11.0±0.6 | 6.7±0.3 |