Table 3.
n before addition of OLST to FRAX | Low risk after addition of OLST to FRAX | High risk after addition of OLST to FRAX | Addends to sum to NRIa | ||
---|---|---|---|---|---|
Participants with fracture during follow-up | Low risk according to FRAX | 34 | 21 | 13 | +13/40 |
High risk according to FRAX | 6 | 2 | 4 | −2/40 | |
Participants without fracture during follow-up | Low risk according to FRAX | 288 | 212 | 76 | −76/309 |
High risk according to FRAX | 21 | 10 | 11 | +10/309 |
The effect of adding one-leg standing time (OLST) to FRAX regarding classification of the study population into a low risk group ≤15% for a hip fracture and a high-risk group with >15% risk. Sensitivity changed from 6/40 to (13 + 4) / 40 = from 15 to 43%. Specificity changed from 288/309 to (212 + 10) / 309 = from 93 to 72%. The positive predictive value changed from 6 / (6 + 21) = 22.2% to (13 + 4) / (13 + 4 + 76 + 11) = 16.3%. The negative predictive value changed from 288 / (288 + 21) = 93% to (212 + 10) / (212 + 10 + 2 + 21) = 91%
aNRI = 13/40−2/40−76/309 + 10/309 = 0.061