Left ventricular (LV) geometry, LV systolic function, infarct size, and LV wall thickness in the infarct areas of WT (n = 4) and TLR9-KO (KO) (n = 4) mice evaluated by cardiac magnetic resonance imaging (MRI) 3 days after myocardial infarction. A: typical cross-sectional images of late gadolinium enhanced cardiac MRI from the apex to the base in end-diastolic phase. Blue area indicates myocardial infarction. Pink area indicates intra-LV cavity. B: quantitative analysis of LV end-diastolic volume, LV end-systolic volume, LV ejection fraction (LVEF), infarct size, and LV wall thickness of the infarct regions. Data were analyzed by Student’s t-test and are expressed as means ± SE.