Table 2.
Left ventricular pressure-volume loop measurements for wild-type and SR-BIΔCT mice
| Maximum Left Ventricular Volume, μl | Minimum Left Ventricular Volume, μl | Cardiac Output, μl/min | Ejection Fraction, % | Stroke Work, mmHg·μl | dP/dtmax, mmHg/s | dP/dtmin, mmHg/s | |
|---|---|---|---|---|---|---|---|
| WT (n = 7) | 45.9 ± 2.4 | 27.2 ± 1.5 | 5.9 ± 0.3 | 31.7 ± 1.3 | 1,703 ± 96 | 8,438 ± 653 | −7,661 ± 630 |
| SR-BIΔCT (n = 6) | 45.3 ± 1.4 | 27.3 ± 0.8 | 5.4 ± 0.3 | 28.8 ± 1.5 | 1,718 ± 116 | 8,638 ± 645 | −8,199 ± 593 |
| P value | >0.05 | >0.05 | >0.05 | >0.05 | >0.05 | >0.05 | >0.05 |
dP/dtmax and dP/dtmin indicate maximal and minimal rate of changes in pressure over time and measure systolic contractility and diastolic relaxation, respectively.