Table 3.
Left ventricular pressure-volume loop measurements for apoE KO and SR-BIΔCT/apoE KO mice
Maximum Left Ventricular Volume, μl | Minimum Left Ventricular Volume, μl | Cardiac Output, μl/min | Ejection Fraction, % | Stroke Work, mmHg·μl | +dP/dt, mmHg/s | −dP/dt, mmHg/s | |
---|---|---|---|---|---|---|---|
apoE KO (n = 6) | 41.5 ± 1.9 | 22.3 ± 1.1 | 6.6 ± 0.5 | 36.5 ± 1.5 | 1,947 ± 137 | 10,737 ± 454 | −8,084 ± 400 |
SR-BIΔCT/apoE KO (n = 8) | 59.5 ± 6.8 | 40.9 ± 4.6 | 4.7 ± 0.3 | 21.0 ± 1.6 | 1,331 ± 120 | 6,404 ± 654 | −5,318 ± 574 |
P value | 0.04 | 0.005 | 0.005 | <0.0001 | 0.006 | 0.0003 | 0.0032 |