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. 2015 Dec 16;13(1):223–227. doi: 10.5114/aoms.2015.56490

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Copyright: © 2015 Termedia & Banach

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.

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Endothelial cell migration (ECM) in response to serum obtained from healthy controls (n = 12) and OSA subjects (n = 12). The ECM in response to serum obtained from healthy individuals shows a diurnal profile with a peak of absorbance measured at 6:00 (*p = 0.02 vs. 21:00, and ^!p = 0.03 vs. 11:00). This pattern was disrupted in OSA patients, in whom chemo-attractant activity was weaker than in normal controls at 21:00 (^#p = 0.02) and at 6:00 (^$p < 0.001), and did not change significantly at the different time-points (p < 0.001 OSA vs. controls)

Data are presented as mean values (bars) with SD (whiskers). T-tests for direct comparisons and ANOVA with repeated measurements for time-related assessment.