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Fig. 7.

Fig. 7.

Transcriptome analysis of IAT in patients with NASH vs. Normal liver phenotype. A: 13,943 transcripts were initially identified (grey dots; RPM > 0, RPKM > 2). 667 were determined to be statistically differentially regulated (black dots; >1.5-fold difference, FDR < 0.10), of which 175 were significantly upregulated and 492 significantly downregulated. B: top 15 individual up- and downregulated transcripts between NASH and Normal. C: top 8 up- and downregulated pathways identified by IPA. D: top 2 canonical pathways identified by IPA using all up- and downregulated genes.