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Table 2.

Subject characteristics

Normal (n = 8) Steatosis (n = 13) NASH (n = 10)
Height, m 1.61 ± 0.03 1.68 ± 0.02 1.67 ± 0.06
Sex, M/F 1/7 4/9 3/7
Body weight, kg 136.0 ± 10.5 148.0 ± 11.8 154.2 ± 13.6
Age at surgery, yr 16.4 ± 0.9 17.1 ± 0.6 17.2 ± 0.4
BMI 51.9 ± 2.9 51.8 ± 3.6 54.7 ± 3.4
BMI z-score 2.6 ± 0.1 2.7 ± 0.1 2.8 ± 0.1
NAS 0 ± 0.0a 1.5 ± 0.2b 4.7 ± 0.4c
Insulin, pg/ml 164.2 ± 48.2 255.6 ± 42.0 566.9 ± 186.9
Glucose, mg/dl 78.9 ± 3.2 82.4 ± 2.6 95.4 ± 10.4
HOMA-IR 0.8 ± 0.3a 1.3 ± 0.2a 3.4 ± 1.0b
Total cholesterol, mg/dl 121.3 ± 4.8 124.9 ± 3.5 126.7 ± 3.2
NEFA, mmol/l 0.36 ± 0.09 0.36 ± 0.06 0.44 ± 0.08
Triglycerides, mg/dl 57.3 ± 5.4a 77.7 ± 8.7a,b 109.7 ± 17.9b

Values are means ± SE. Different letter superscripts are significantly different (P < 0.05).

BMI, body mass index; NAS, nonalcoholic fatty liver disease (NAFLD) activity score; HOMA-IR, homeostatic model assessment/insulin resistance; NEFA, nonesterified fatty acids.