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. 2016 Nov 4;48(12):936–949. doi: 10.1152/physiolgenomics.00111.2016

Fig. 5.

Fig. 5.

Whole body lipid metabolism in HFD-fed WT and Ctrp12 (+/−) male mice. A: serum total cholesterol, triglyceride (TG), LDL-cholesterol, and HDL-cholesterol levels in WT and Ctrp12 (+/−) male mice. Food was removed 4 h before serum collection. Serum levels of TG (B) and the corresponding area under curve (C), NEFA (D), and total cholesterol (E) in WT and Ctrp12 (+/−) male mice at 0, 1, 2, 3, and 4 h following an oral gavage of 20% Intralipid in a lipid tolerance test (LTT). Mice were overnight fasted (16 h) before oral lipid gavage. Serum levels of TG (F) and total cholesterol (G) in WT and Ctrp12 (+/−) male mice at 0, 1, 2, 6, and 9 h following injection of Poloxamer 407 (1 g/kg body wt). Food was removed 4 h before Poloxamer injection. Liver TG (H) and cholesterol (I) levels in WT and Ctrp12 (+/−) male mice. J: serum ketone levels in 4 h fasted WT and Ctrp12 (+/−) male mice (n = 11–16 per group). *P < 0.05; **P < 0.01.