Table 4.

Physiological and cardiac Doppler imaging results

Variable	ShamA (n = 9)	ShamS (n = 8)	PNxA (n = 5)	PNxS (n = 10)
Heart rate, beats/min	335 ± 9	339 ± 8	365 ± 10	347 ± 8
LVW/BW, g/kg	2.10 ± 0.05	2.20 ± 0.04	2.47 ± 0.04	2.82 ± 0.11
Final BW, g	367 ± 9	331 ± 9	337 ± 10	325 ± 8
Final HW, mg	954 ± 28	897 ± 23	998 ± 51	1091 ± 44
LVW, mg	769 ± 23	727 ± 15	835 ± 38	917 ± 44
KW, g	1.30 ± 0.27	1.03 ± 0.03	1.58 ± 0.12	1.39 ± 0.05
EDV, μl	208 ± 10	181 ± 12	204 ± 12	165 ± 10
ESV, μl	56 ± 2	37 ± 5	41 ± 5	18 ± 5
WTI	0.39 ± 0.01	0.42 ± 0.03	0.42 ± 0.03	0.52 ± 0.02
EF, %	73 ± 1	80 ± 2	80 ± 2	89 ± 2
VCF, s−1	0.76 ± 0.03	0.77 ± 0.03	0.88 ± 0.07	0.92 ± 0.07
Tei index	0.69 ± 0.02	0.69 ± 0.02	0.75 ± 0.07	0.78 ± 0.04

Data presented in this table are: heart rate, left ventricle hypertrophy [LVW (g) to BW (kg) ratio], final body weight in g, final heart weight in mg, LVW in mg, KW in g, end-diastolic volume (ml), end-systolic volume (ml), wall thickness index, ejection fraction, velocity of circumferential shortening, and Tei index, as determined prior to sacrifice by echocardiography. Means ± SE are shown from measurements in n = 9 ShamA, 8 ShamS, 5 PNxA, and 10 PNxS animals. Data analyze with 2-way ANOVA, results of analyses found in Table 5. Abbreviations: LVW, left ventricle weight; BW, body weight; HW, heart weight; KW, kidney weight; EDV, end-diastolic volume; ESV, end-systolic volume; WTI, wall thickness index; EF, ejection fraction; VCF, velocity of circumferential shortening; Tei index, myocardial performance index; ShamA, sham operated room air exposure only (no combustible cigarette exposure); ShamS, sham-operated exposed to 5 cigarettes per day 5 days per week for 4 wk; PNxA, 5/6th partial nephrectomy room air exposure only (no combustible cigarette exposure); PNxS, 5/6th partial nephrectomy exposed to 5 cigarettes per day 5 days per week for 4 wk.