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. 2016 Dec 20;2016:6253280. doi: 10.1155/2016/6253280

Figure 1.

Figure 1

Emodin suppressed the proliferation, migration, and invasion property of A2780 and SK-OV-3cells. (a) SK-OV-3 cells and A2780 cells were treated with increased concentrations of emodin for up to 72 hours to examine the cell viability. 24 h: ∗ P < 0.05, ∗∗ P < 0.005; 48 h: # P < 0.05, ## P < 0.005, and ### P < 0.001; 72 h: ∗ P < 0.05, ∗∗ P < 0.005, and ∗∗∗ P < 0.001. (b) Emodin inhibited A2780 and SK-OV-3 cells growth in the dose- and time-dependent fashion. ∗ P < 0.05, ∗∗ P < 0.005, and ∗∗∗ P < 0.001. (c) Representative transwell migration and invasion assay of SK-OV-3 cells and A2780 cells after treatment with emodin (×200 magnification). (d) Emodin weakened migration and invasion capacity of A2780 and SK-OV-3 cells. ∗ P < 0.05, ∗∗ P < 0.005, and ∗∗∗ P < 0.001.