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. 2017 Jan;214(1):125–142. doi: 10.1084/jem.20160470

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© 2017 Connor et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 2. — Expression of genes involved in DC function after immunization with Nb or DBP-FITC. LN were collected from C57BL/6 mice immunized with 600 Nb, DBP-FITC, or mock treated. DC subsets were flow sorted as in Fig. S1 for RNA preparation and sequencing. Heat maps on the left show the levels of expression of genes associated with different DC functions or with the induction of Th2 immune responses as indicated. Differential expression analysis in treated groups is on the right. DC expression data are the mean of three replicate samples each from an independent experiment for each Th2 condition. P-values were calculated by DESeq2; *, P < 0.05; **, P < 0.01; ***, P < 0.001.