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. 2016 Dec 12;113(52):15126–15131. doi: 10.1073/pnas.1611023114

Fig. S3.

Fig. S3.

CCR2 inhibition and CCR2KO BMT reduce leukocyte infiltration into the heart following MI. (A) Representative CD68, tryptase, and MPO staining for the remote zone of hearts from WT C57BL/6 mice that underwent MI surgery followed by administration (i.p.) of 2 mg⋅kg−1⋅d−1 of a CCR2 antagonist or vehicle for 4 d or WT C57BL/6 mice receiving WT, β2ARKO, or CCR2KO BMT animals that underwent MI surgery. (B–D) Quantification of CD68 (B), tryptase (C), and MPO (D) staining for the remote zone of 4-d post-MI hearts from Veh- and CCR2 antagonist-treated mice or WT, β2ARKO, and CCR2KO BMT animals. n = 4–8. Data are expressed as mean ± SEM.