Table 5. Differential clinical laboratory factors at first presentation among dengue patients with severe organ involvement outcome compared against matched dengue patients with no severe organ involvement outcome.

	Controls^ (N = 865)	Interquartile range	Cases (N = 174)	Interquartile range	AcOR*	p-value	95% CI	95% CI
Median WBC	2.7	(2–3.8)	3.3	(2.1–4.7)	1.18	<0.0001	1.09	1.27
Median neutrophil	53.8	(40.6–67.2)	61.7	(50–70)	1.02	<0.0001	1.01	1.03
Median lymphocytes	26	(18.5–35.2)	20.2	(15–28.9)	0.96	<0.0001	0.95	0.98
Median monocytes	10	(6.9–13.1)	8.6	(5.4–12.8)	0.97	0.14	0.94	1.01
Median basophils	0.2	(0–0.6)	0.2	(0–0.5)	0.89	0.541	0.61	1.3
Median eosinophil	0.2	(0–1)	0.1	(0–0.5)	0.84	0.047	0.7	0.99
Median hematocrit	43.1	(40–45.8)	44	(40–46.9)	1.06	0.001	1.01	1.11
Median hemoglobin	14.6	(13.5–15.6)	15	(13.6–16)	1.2	0.006	1.06	1.37
Median platelet	70	(47–87)	51	(25–73)	0.98	<0.0001	0.98	0.99
Median sodium	137	(134–139)	135	(132–137)	0.84	<0.0001	0.8	0.88
Median potassium	3.6	(3.3–3.9)	3.6	(3.3–4)	1.41	0.092	0.95	2.09
Median urea	3.4	(2.5–4.4)	4.3	(2.8–7.4)	1.42	<0.0001	1.29	1.57
Median creatinine	76	(62–88.5)	85	(65.3–128.3)	1.03	<0.0001	1.02	1.04
Median bilirubin	11	(8–15)	13	(9–18)	1.06	<0.0001	1.04	1.09
Median AST	112.5	(65–207.3)	771	(174–1242)	1	<0.0001	1.004	1.006
Median ALT	71	(39–148)	389	(91.5–717)	1.006	<0.0001	1.005	1.008
Median protein	68	(64–72)	66	(61–71)	0.96	0.016	0.93	0.99
Median albumin	39	(36–41)	37	(33–40)	0.89	<0.0001	0.85	0.934

WBC - White blood cells.

AST - Aspartate aminotransferases.

ALT - Alanine aminotransferases.

^{^}Matched by year of presentation as the surrogate marker to minimize the impact of different predominant serotypes of that year.

^*Adjusted by age group, gender, day post fever duration at presentation, diabetic, hypertension, hyperlipidemia, cardiac disorder and asthma.