Chronic fluoxetine administration does not reverse TBI-induced impairment in gait spatial parameters. The intensity (A) and maximum areas (B) were reduced at all paws at 5 weeks following TBI. Fluoxetine did not have any effect on either intensity or maximum area in sham or brain-injured mice (NS, not significant between TBI/vehicle-treated and TBI/fluoxetine-treated groups; TBI, traumatic brain injury; Fluox, fluoxetine; RF, right fore; RH, right hind; LF, left fore; LH, left hind; a.u., arbitrary units).