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. 2017 Jan 3;7:39501. doi: 10.1038/srep39501

Figure 5. Plumericin, PHA-408, and NAC inhibit TNFα-induced cell-cycle arrest in HUVECs.

Figure 5

(a) Growth curves of HUVECs treated with TNFα ± inhibitors in comparison to control HUVECs for indicated time points. (b,d) Quantification of staining for (b) Ki-67, (c) p21 and (d) p16 of HUVECs treated with TNFα ± inhibitors in comparison to control HUVECs ± inhibitors at day nine. Values are presented as mean ± SD of technical triplicates. (*p < 0.05, **p < 0.01, ***p < 0.001). The results shown are representative of three independent experiments. C: control, PL: plumericin, PHA: PHA-408, NAC: N-acetyl cysteine.