Table 3. Comparison of flux ranges, reaction essentialities and metabolite producibilites in ECC2 and ECGS for growth on glucose.
Property | Proportions |
---|---|
Flux ranges (under growth-optimality; Fi is the difference of maximal and minimal flux of reaction i) | |
290/499 (58.1%) | |
153/499 (30.7%) | |
| | 29/499 (5.8%) |
27/499 (5.4%) | |
Essentialities of reactions | |
Essential for growth (ECC2/ECGS) | 411/290 |
● for protected reactions (ECC2/ECGS) | 7/6 |
Not essential for growth but growth-rate limiting (ECC2/ECGS) | 17/16 |
● for protected reactions (ECC2/ECGS) | 8/7 |
No effect, growth rate >95% of μmax (ECC2/ECGS) | 71/193 |
● for protected reactions (ECC2/ECGS) | 50/52 |
Producibilities of metabolites | |
Maximal product yield in ECC2 >95% of maximal product yield in ECGS | 378/486 (77.8%) |
Maximal product yield in ECC2 >80% and <95% of maximal product yield in ECGS | 55/486 (11.3%) |
Maximal product yield in ECC2 <80% of maximal product yield in ECGS | 53/486 (10.9%) |
Comparisons were restricted to those reactions and internal metabolites that are present in ECC2.