FIGURE 1.

Brain circuits in cognitive interventions in addiction. Common results across intervention modalities were the normalization of aberrant activity in the brain’s reward circuitry, and the recruitment and strengthening of the brain’s inhibitory control network (regions involved in reward processing are depicted in red (light gray in the print version): e.g., striatum; NAcc, nucleus accumbens; VTA, ventral tegmental area; inhibitory control network is shown in blue (dark gray in the print version): e.g., IFG, inferior frontal gyrus; dACC, dorsal anterior cingulate). During motivational interventions regions involved in self-referential processing and motivated attention were activated (in green (light gray in the print version): mPFC, medial prefrontal cortex; PCC, posterior cingulate cortex, precuneus).