Table 1.
Measured values for disc weight, size dimensions, percent moisture, pH, % non-protonated nicotine, and total nicotine concentrations in unused ONDP discs.
Parameters for unused ONDP discs | Average values (±SD) |
---|---|
Disc weight (mg)a | 493.0 ± 12.8 |
Percent moisturea | 8.40 ± 0.05 |
pHb | 7.47 ± 0.09 |
Nicotine (mg/disc, stated on packaging)c | 1.50 |
Measured total nicotine (mg/disc)b | 1.68 ± 0.09 |
% of nicotine as non-protonated nicotine (at pH 7.47) | 22.1% |
Non-protonated nicotine (mg/disc at pH 7.47)b | 0.37 |
ONDP = oral nicotine delivery product.
n = 5.
n = 4.
n = 3.