Table 3.
Correlation between liver fibrosis markers and each of liver function index, serum inflammatory markers, hepatic oxidative stress and apoptosis among studied groups
| Fibrosis markers | Liver function | Inflammatory markers | Oxidative stress markers | Apoptotic markers | ||||
|---|---|---|---|---|---|---|---|---|
| ALT | IL‐1β | IL‐1β/IL‐10 | MDA | GSH | CAT | Caspase‐3 | BCL2 | |
| Hyp | r = 0.99a | r = 0.97a | r = 0.95a | r = 0.98a | r = −0.97a | r = −0.99a | r = 0.98a | r = −0.99a |
| Collagen area% | r = 0.99a | r = 0.98a | r = 0.97a | r = 0.98a | r = −0.95a | r = −0.99a | r = 0.98a | r = −0.99a |
| MMP‐9 | r = 0.99a | r = 0.99a | r = 0.99a | r = 0.98a | r = −0.96a | r = −0.99a | r = 0.98a | r = −0.98a |
| TIMP‐2 | r = −0.95a | r = −0.95a | r = −0.91a | r = −0.97a | r = 0.96a | r = 0.95a | r = −0.96a | r = 0.96a |
| ECM turnover marker (MMP‐9/TIMP‐2mRNA) | r = 0.97a | r = 0.99a | r = 0.99a | r = 0.94a | r = −0.92a | r = −0.97a | r = 0.96a | r = −0.95a |
a
Significant at P < 0.0001.