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. Author manuscript; available in PMC: 2018 Jan 2.
Published in final edited form as: Angew Chem Int Ed Engl. 2016 Dec 2;56(1):212–216. doi: 10.1002/anie.201609452

Figure 1. The application and synthesis of AcdK.

Figure 1

(A) Structures of AlK and AcdK. (B) A diagram that illustrates the genetic incorporation of AcdK followed by Staudinger reduction, self-cleavage of the para-aminobenzyloxycarbonyl group, enamine hydrolysis, and reductive amination to generate a dimethyllysine in a protein. (C) The synthesis of AcdK. It starts with L-glutamate and finishes with a dilithium salt of AcdK.