Table 3.
Within group partial correlations between brain ROIs (left, right) and clinical measures, controlling for wbv, age, and htn; GAD group.
| Lamyg | Ramyg | Ldlpfc | Rdlpfc | LmOFC | RmOFC | PSWQ | BDI | STAI | Onset | |
|---|---|---|---|---|---|---|---|---|---|---|
| Lamyg | – | 0.388 | 0.199 | −0.476 | −0.099 | 0.234 | −0.471 | −0.371 | −0.261 | −0.179 |
| Ramyg | – | 0.120 | −0.143 | 0.119 | 0.271 | −0.040 | −0.073 | −0.159 | 0.309 | |
| Ldlpfc | – | 0.592 | −0.264 | −0.204 | −0.190 | 0.084 | −0.007 | 0.371 | ||
| Rdlpfc | – | 0.206 | 0.058 | 0.467 | 0.409 | 0.122 | 0.348 | |||
| LmOFC | – | 0.879** | 0.872** | 0.459 | 0.513 | −0.022 | ||||
| RmOFC | – | 0.661 | 0.195 | 0.373 | 0.168 | |||||
| PSWQ | – | 0.579 | 0.538 | 0.199 | ||||||
| BDI | – | 0.427 | 0.090 | |||||||
| STAI | – | 0.159 |
Note.
P<0.001.
amyg=amygdala; dlpfc=dorsolateral cortex; mOFC=medial orbital cortex; wbv=whole brain volume; PSWQ=Penn State Worry Questionnaire; BDI=Beck Depression Inventory; STAI=Trait Scale, State Trait Anxiety Inventory; Onset=age of GAD onset. All brain volumes were measured in cubic centimeters, without cerebrospinal fluid.