Table 2.
Effect of 28-day administration of methanol leaf extract of D. saxatilis on renal indices
| Electrolytes | Control | 250mg/kg | 500mg/kg | 1000mg/kg |
|---|---|---|---|---|
| Urea (mmol/l) | 10.38±1.35 | 15.46 ± 2.66 | 14.70 ± 1.42 | 15.80 ± 2.68 |
| Creatinine(μmol/l) | 47.69 ± 6.06 | 65.05 ± 5.04 | 59.59 ± 2.59 | 61.13 ± 4.54 |
| Chloride (mmol/l) | 122.60±4.06 | 105.00 ± 4.56a | 107.00 ± 4.64a | 111.75 ± 2.96 |
| Sodium (mmol/l) | 168.80±7.74 | 139.00 ± 7.15a | 141.20 ± 5.98a | 146.00 ± 4.51 |
| Potassium(mmol/l) | 5.56±0.27 | 5.95 ± 0.63 | 5.50 ± 0.32 | 5.35 ± 0.18 |
| Bicarbonate (mmol/l) | 28.80±2.25 | 18.50 ± 1.56a | 20.80 ± 1.63 | 21.00 ± 1.16 |
Data are presented as mean ± SEM, and analyzed using one way ANOVA followed by Dunnett t-test.
‘a’
in superscript represent p< 0.05. n = 5.