Figure 5. ZF-KRAB proteins reduce the growth of BCL6-dependent lymphoma cells.
A) Cell growth of Tet-inducible ZFe1-KRAB or ZFp-KRAB expressing OCI-Ly7 cells (BCL6-dependent) cultured with or without doxycycline was measured by Trypan blue exclusion. Results represent the mean ± SD of three independent experiments. **** p < 0.0001 B) Cell growth of Tet-inducible ZFe1-KRAB expressing BCL6-dependent or -independent cells measured as in A.