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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Leuk Lymphoma. 2016 Jun 7;58(2):445–456. doi: 10.1080/10428194.2016.1190973

Figure 6. ZF-KRAB proteins induce apoptosis in BCL6-dependent lymphoma cells.

Figure 6

A) Number of OCI-Ly7 cells with active Caspase-3 staining measured by flow cytometry. OCI-Ly7 cells harboring Tet-inducible ZFe1- or ZFp-KRAB were cultured for four days with or without doxycycline. Representative of three independent experiments. B) Percentage of cells with active Caspase-3 staining measured by flow cytometry. OCI-Ly7 cells (BCL6-dependent) harboring Tet-inducible ZFe1-KRAB or ZFp-KRAB were cultured and treated as in (A). Results represent the mean ± SD of three independent experiments. ** p < 0.01 *** p < 0.001**** p < 0.0001