Table 4.
Comparison of the SP-A, SP-B and SP-D serum levels in different genotypes of SP-A, SP-B and SP-D genes between the infants with respiratory distress syndrome (case group) and infants without respiratory distress syndrome (control group).
SNP | Genotypes | Case group (ng/ml) | Control group (ng/ml) |
---|---|---|---|
SP-A +186A/G | AA | 110.67±2.52 | 112.64±2.13* |
AG | 110.27±2.31 | 113.05±1.85* | |
GG | 111.20±2.16 | 114.70±1.75* | |
SP-A +655C/T | CC | 110.68±2.51 | 112.67±2.25* |
CT | 110.08±2.30 | 113.14±1.72* | |
TT | 111.70±1.76 | 114.60±1.70* | |
SP-B −18A/C | CC | 109.74±3.52 | 110.74±2.47 |
CA | 109.69±5.34 | 111.22±2.16 | |
AA | 109.66±5.67 | 111.10±2.26 | |
SP-B 1580C/T | CC | 109.53±4.45 | 111.42±1.99* |
CT | 108.31±5.28 | 110.94±2.12* | |
TT | 114.01±1.94 | 110.41±3.01* | |
SP-D Met11ThrT/C | TT | 112.27±4.99 | 111.16±2.00 |
TC | 111.43±3.60 | 111.10±2.79 | |
CC | 110.08±2.65 | 111.73±3.30 | |
SP-D Ala160ThrG/A | GG | 110.88±3.30 | 111.71±2.62 |
GA | 111.96±3.00 | 110.54±3.45 | |
AA | 110.75±2.72 | 112.92±2.23 |
Compared with the control group, P<0.05;
SNP – single nucleotide polymorphism.