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. 2016 Dec 26;22:5131–5140. doi: 10.12659/MSM.898095

Table 3.

Correlation of SMYD3 VNTR polymorphism with clinic-pathologic characteristics of patients.

Clinical charateristics 2/2+2/3 3/3 OR value (95%CI) P
Age (age) 0.309
 <45 13 (39.4%) 37 (30.1%) 1 (reference)
 ≥45 20 (60.6%) 86 (69.9%) 0.662 (0.298–1.470)
First menstruation (age) 0.699
 <13 16 (48.5%) 55 (44.7%) 1 (reference)
 ≥13 17 (51.5%) 68 (55.3%) 0.859 (0.398–1.856)
First childbearing age 0.399
 <20 15 (45.5%) 46 (37.4%) 1 (reference)
 ≥20 18 (54.5%) 77 (62.6%) 0.717 (0.329–1.559)
Last childbearing age 0.988
 <40 19 (57.6%) 71 (57.7%) 1 (reference)
 ≥40 14 (42.4%) 52 (42.3%) 1.006 (0.462–2.190)
Mesntruation codition 0.508
 Premenopause 24 (72.7%) 82 (66.7%) 1 (reference)
 Postmenopause 9 (27.3%) 41 (33.3%) 0.750 (0.319–1.760)
Abortion history 0.333
 No 23 (69.7%) 80 (65.0%) 1 (reference)
 Yes 10 (30.3%) 43 (35.0%) 1.545 (0.637–3.748)
Tumor classification
 HGSC 17 (51.5%) 79 (64.2%) 1 (reference)
 EC 4 (12.1%) 13 (10.6%) 1.105 (0.327–3.729) 0.872
 CCC 5 (15.2%) 13 (10.6%) 1.381 (0.444–4.296) 0.576
 MC 5 (15.2%) 14 (11.4%) 1.282 (0.416–3.952) 0.664
 LGSC 2 (6.0%) 4 (3.2%) 1.795 (0.308–10.46) 0.509
Tumor differentiation 0.017
 Middle/high differentiation 29 (87.9%) 89 (72.3%) 1 (reference)
 Low differentiation 4 (12.1%) 44 (35.7%) 3.584(1.186–10.840)
FIGO staging 0.045
 I–II 27 (81.8%) 78 (63.4%) 1 (reference)
 III–IV 6 (18.2%) 45 (36.6%) 0.385 (0.148–1.004)

P value was detected by Wilcoxon rank-sum test; OR – odd ratio; CI – confidence interval; EC – endometrial carcinoma; CCC – clear cell carcinoma; MC – mucin-like cell carcinoma; HGSC – high-grade serous adenocarcinoma; LGSC – low-grade serous adenocarcinoma; FIGO – International Federation of Gynecology and Obstetrics.