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. Author manuscript; available in PMC: 2017 Jan 3.
Published in final edited form as: Biochem Biophys Res Commun. 2016 Jul 25;478(2):559–564. doi: 10.1016/j.bbrc.2016.07.100

Fig. 1. Rat 125I-Ang-(1-2) and 125I-Ang I substrate hydrolysis by PMs isolated from SHR heart.

Fig. 1

Chromatograms show the 125I-Ang II product generation from 125I-Ang-(1-12) and 125I-Ang I by PMs isolated from the SHR heart. Panel A and B: In the presence of all RAS inhibitors (including chymostatin and lisinopril). Panel C and D: In the absence of chymostatin (chymase inhibitor) only. Panel E and F: In the absence of lisinopril (ACE inhibitor) only. Results are representative of three or more separate metabolism experiments for each group.