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. Author manuscript; available in PMC: 2017 Oct 15.
Published in final edited form as: Cancer Res. 2016 Aug 28;76(20):6095–6106. doi: 10.1158/0008-5472.CAN-16-0709

Figure 1.

Figure 1

miR-22 and -378 are downregulated in RMS but are induced during myogenic differentiation. A, section of the expression dendrogram including the top 8 differentially expressed miRNAs in human skeletal muscles compared to RMS cells and tissues. Yellow indicates increased expression; black indicates reduced expression. B, Northern blot analysis on total RNA obtained from one muscle and one RMS sample. C and D, real-time PCR analysis in murine satellite cells (C) and C2C12 cells (D) grown in proliferation ‘P’ or differentiation medium ‘D’. E and F, real-time PCR analysis in inducible miR-206-expressing RD18 (NpBI-206) cells (E) and MyoD-expressing NIH 10T½ (NpBI-MyoD) cells (F) (induced, IND; non-induced, NI). Error bars, SD.