Skip to main content
. 2016 Oct 31;291(50):26177–26187. doi: 10.1074/jbc.M116.743906

FIGURE 2.

FIGURE 2.

PIs promote the innate immune response without causing global T cell activation. A, surface markers of T cell CD25 and CD69 of PBMCs were detected by FCM after treatment for 24 h with BTZ and CFZ. Prostratin (1 μm) was used as a positive control. B, the mRNA expression of surface markers and immune cytokines were analyzed by qPCR after treating with PIs and prostratin for 12 h. C and D, the secretion of IL-1β and IL-18 were measured by ELISA after treatment for 24 h. *, p < 0.05; **, p < 0.01; and ***, p < 0.001 versus control.